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Relationship Between BMI and Prediabetes in Chinese Adults: A Cross-Sectional Analytical Study
Beibei Luo1, Wenbo Xu1, Dan Ye1
1Clinical Laboratory, People's Hospital of Yuxi City, The Sixth Affiliated Hospital of Kunming Medical University, 21 Nieer Road, Yuxi, Yunnan 653100, China.
International Journal of Endocrinology
|October 22, 2025
Summary
Higher body mass index (BMI) significantly increases prediabetes risk in Chinese adults. Obesity is a key factor, highlighting the need for weight management to prevent diabetes progression.
Area of Science:
- Public Health
- Epidemiology
- Metabolic Health
Background:
- Prediabetes is a critical precursor to type 2 diabetes.
- Limited research exists on the specific impact of body mass index (BMI) on prediabetes risk within the Chinese population.
Purpose of the Study:
- To investigate the association between body mass index (BMI) and the risk of developing prediabetes among Chinese adults.
Main Methods:
- Cross-sectional analytical study utilizing data from 11,847 participants in the 2011 China Health and Retirement Longitudinal Study (CHARLS).
- Logistic regression models were used for univariate and multivariate analyses.
- Odds ratios (OR) and 95% confidence intervals (95% CI) were calculated for various BMI categories relative to a reference range (18.5-23.9 kg/m²).
Main Results:
- Significant differences in demographic, lifestyle, and clinical variables were observed across BMI groups (p < 0.05).
- Curve fitting analysis revealed that prediabetes risk increases when BMI exceeds 22.9 kg/m².
- Higher BMI categories showed a greater prevalence of prediabetes.
Conclusions:
- Obesity is identified as a significant risk factor for prediabetes.
- The prevalence of prediabetes is notably higher in overweight and obese individuals in China.
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