Related Experiment Video
Updated: Jan 14, 2026

Establishment of the Dual Humanized TK-NOG Mouse Model for HIV-associated Liver Pathogenesis
Published on: September 11, 2019
Disseminated cryptococcosis in an HIV patient with hepatitis C as the associated risk factor
Pallavi Dhawan1, Varsha Gupta1, Monica Gupta2
1Department of Microbiology, Government Medical College Hospital, Chandigarh, India.
Background And Purpose:
In the context of HIV/AIDS, cryptococcosis emerges as one of the most common opportunistic infections, with a predilection for affecting individuals with compromised immune function.
Case Report:
This study aimed to present a compelling case of disseminated cryptococcosis in a 29-year-old male with a complex medical history, marked by HIV infection, hepatitis C, and a longstanding history of intravenous drug abuse. Blood sample of the patient as well as the cerebrospinal fluid sample grew Cryptococcus neoformans. Immunochromatographic test performed on CSF and serum sample was also positive.
Conclusion:
Chronic Hepatitis C Virus can disrupt the blood-brain barrier and cause neuroinflammation predisposing the central nervous system to hematogenous seeding during fungemia. Multifaceted medical background of the patient underscored the challenges in the management of comorbidities.
Related Concept Videos
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Sexually Transmitted Infections
Retrovirus Life Cycles
Immunodeficiency Diseases
There are three main causes of immunodeficiency...

