Yellow Fever Vaccine-Associated Viscerotropic Disease: A Unique Case of Atraumatic Splenic Rupture

Atraumatic splenic rupture is an uncommon, life-threatening abdominal emergency involving the rupture of the spleen in the absence of obvious trauma. This case report provides a summary of a 48-year-old male who presented to the Emergency Department of the University of Ghana Medical Centre with syncope and hemodynamic instability one week after receiving a yellow fever vaccine. A diagnosis of an atraumatic splenic rupture was eventually confirmed by imaging, and a splenectomy was done. This report aims to provide valuable insights into the recognition and management of atraumatic splenic rupture, a potential adverse event associated with the yellow-fever vaccine. It also highlights the importance of prompt diagnosis and timely intervention in such life-threatening cases.