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Boosting Conductive Bioplastic Applications with SpyCatcher-SpyTag Technology and Cellulose Scaffolds
Ji Hyun Lee1, Eun Seo Lee2, Un Jung Chae2
1Department of Next Generation Applied Sciences, Graduate School, Sungshin Women's University, Seoul 01133, Republic of Korea.
Biomacromolecules
|October 22, 2025
Summary
Researchers developed a novel conductive bioplastic using engineered proteins and bacterial cellulose. This eco-friendly material shows significantly enhanced electrical conductivity for sustainable electronic applications.
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Biotechnology
Background:
- Conventional plastics pose environmental challenges.
- Bioplastics offer sustainable alternatives.
- Developing conductive bioplastics expands their functional applications.
Purpose of the Study:
- To engineer a novel conductive bioplastic material.
- To enhance the electrical conductivity and stability of bioplastics.
- To explore applications in sustainable electronic devices.
Main Methods:
- Recombination of SpyCatcher-SpyTag system with leghemoglobin (GmLegC2) to create functional proteins.
- Assembly of proteins into a conductive polymer.
- Fusion of engineered protein with carbohydrate-binding module and integration into bacterial cellulose scaffolds.
Main Results:
- The resulting protein-hemin mixture showed 2.5x higher conductivity than free hemin.
- The composite material integrated into bacterial cellulose scaffolds exhibited a 141-fold increase in conductivity.
- The composite demonstrated uniform and stable electrical performance.
Conclusions:
- Developed an eco-friendly conductive bioplastic with significantly enhanced conductivity and stability.
- The material shows great potential for wearable sensors, electronic devices, and sustainable conductive materials.
- This work contributes to advancing sustainable materials for next-generation electronics.

