Related Experiment Video
Updated: Jan 14, 2026

Age-dependent Dynamics of Locomotion in Caenorhabditis elegans: A Lyapunov Exponent Analysis
Published on: September 23, 2025
Strongly nonlinear age-structured equation, time-elapsed model and large delays
Benoît Perthame1, Clément Rieutord2, Delphine Salort3
1Sorbonne Université, CNRS, Université de Paris Cité, Inria, Laboratoire Jacques-Louis Lions, LJLL, EPC MUSCLEES, F-75005, Paris, France. benoit.perthame@sorbonne-universite.fr.
Abstract:
The time-elapsed model for neural assemblies is a nonlinear age-structured equation where the renewal term describes the network activity and influences the discharge rate, possibly with a delay due to the length of connections. We first solve a long standing question, namely that an inhibitory network without delay can promote desynchronization and stabilizes network activity by proving rigorously that the solution converges to a unique steady state. Our approach is based on the observation that a non-expansion property holds. However a non-degeneracy condition is needed and, besides the standard one, we introduce a new condition based on strict nonlinearity. When a delay is included, following previous works for Fokker-Planck models, we prove that the network can generate periodic solutions, both in inhibitory and excitatory networks. To this end, we introduce a new formalism to establish rigorously this property for large delays. Moreover, the fundamental contraction property can extend to other age-structured equations and systems.
Related Concept Videos
Linear Approximation in Time Domain
For a simple pendulum with a mass evenly distributed along its length and the center of mass located at half the pendulum's length,...
Exponential Equations for Modeling Growth
Modeling with Differential Equations
Exponential Equations with Logarithms: Problem Solving
Linear Approximation in Frequency Domain
In contrast, nonlinear systems do not inherently possess these properties. However, for small deviations around an operating point, a nonlinear system can often be approximated as linear....
Linear time-invariant Systems
The input-output behavior of an LTI system can be fully defined by its response to an impulsive excitation at its input. Once this impulse response is known, the system's reaction to any other input can be...

