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Updated: Jan 14, 2026

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Revisiting evolutionary rate-time relationships.

Stephen P De Lisle1, Erik I Svensson2

  • 1Department of Environmental and Life Science, Karlstad University, Universitetsgatan 2, 651 88, Karlstad, Sweden.

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|October 22, 2025
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Summary
This summary is machine-generated.

Evolutionary rates often appear to slow down over time, but this is usually an artifact of how rates are calculated. True evolutionary rate-time relationships are difficult to interpret and often unrelated to time itself.

Keywords:
evolutionary ratemacroevolutionmicroevolutionstasis paradox

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Area of Science:

  • Evolutionary biology
  • Quantitative biology

Background:

  • Evolutionary rates (molecular, phenotypic, lineage) often show negative scaling with measurement time.
  • This temporal scaling has raised questions about the time-dependency of evolutionary processes.

Purpose of the Study:

  • To revisit challenges in interpreting rate-time relationships in evolutionary biology.
  • To investigate the inevitability and interpretation of negative rate-time scaling.

Main Methods:

  • Simulations of evolutionary processes under constant rates.
  • Reanalysis of six empirical evolutionary datasets.
  • Break-point regression to test for modes of evolutionary change across timescales.

Main Results:

  • Negative rate-time scaling is often an artifact of plotting ratios against time.
  • Simulations show constant rates readily produce negative scaling.
  • Empirical data show evolutionary magnitudes are often time-unrelated; >99% of rate-time variation explained by time alone.
  • No strong support found for a hypothesis of three distinct evolutionary modes across timescales.

Conclusions:

  • Negative rate-time relationships are largely inevitable and difficult to interpret.
  • Assessing the accumulation of evolutionary change over time is more straightforward than interpreting rate-time scaling.