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[Therapy of ankylosing spondylitis]
Summary
Ankylosing spondylarthritis management focuses on controlling disease progression and preventing severe lesions through complex chemo- and physiotherapy. Early diagnosis and comprehensive care, including chloroquine, significantly reduce invalidisation rates.
Area of Science:
- Rheumatology and Immunology
- Inflammatory Arthropathies
Context:
- Ankylosing spondylarthritis (AS) lacks a causal therapy due to unknown etiology.
- Management strategies aim to control disease progression and prevent irreversible joint damage.
Purpose:
- To outline current treatment approaches for ankylosing spondylarthritis.
- To highlight the efficacy of combined chemo- and physiotherapeutic measures.
- To emphasize the role of early diagnosis and comprehensive patient care.
Summary:
- Complex treatment regimens involving chemotherapy and physiotherapy can effectively control AS progression.
- Chloroquine has shown promise as a foundational therapy.
- Optimized dispensary care, regular monitoring, and rehabilitation measures have drastically reduced invalidisation rates from 50% to 10%.
Impact:
- Early detection in the prodromal phase offers hope for preventing severe morphological lesions.
- Reduced invalidisation rates signify improved patient outcomes and quality of life.
- This approach underscores the importance of multidisciplinary care in managing chronic inflammatory diseases.