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Updated: Jan 14, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Partial arch replacement for type A aortic dissection with cold agglutinin disease after sutimlimab
Tatsuya Ozaki1, Taro Nakazato1, Koji Hashimoto2
1Department of Cardiovascular Surgery, Kansai Rosai Hospital, Hyogo, Japan.
Sutimlimab effectively managed cold agglutinin disease (CAD) in a patient undergoing aortic surgery with hypothermic circulatory arrest. This approach prevented hemolysis, allowing for an uneventful recovery and discharge.
Area of Science:
- Cardiovascular Surgery
- Hematology
- Immunology
Background:
- Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia.
- CAD poses significant risks during aortic surgery requiring hypothermic circulatory arrest due to potential hemolysis.
- Established perioperative management guidelines for CAD patients undergoing such procedures are lacking.
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