Related Experiment Video
Updated: Jan 14, 2026

High Content Screening in Neurodegenerative Diseases
Published on: January 6, 2012
Hunter-Schreger Bands: Clinical Implications and Future Directions, Scoping Review
Mario Dioguardi1, Ciro Guerra1, Gaetano Illuzzi1
1Department of Clinical and Experimental Medicine, University of Foggia, Via Rovelli 50 71122, Foggia, Italy.
None:
This scoping review aims to examine and identify the potential clinical implications and future research directions concerning Hunter-Schreger bands (HSBs) through an analysis of the scientific medical literature. The scoping review was conducted following the PRISMA Extension for Scoping Reviews (PRISMA-ScR) guidelines, utilising electronic databases such as PubMed, Scopus, the Cochrane Central Register of Trials and ScienceDirect, employing keyword combinations for database search. During the selection process, 327 records were identified, of which only 10 studies fully met the inclusion criteria and were included in the review. The extracted data were summarised in tables. Current evidence suggests that HSB play a crucial role in strengthening enamel by dissipating energy and preventing crack propagation. The use of imaging technologies, optical microscopy and diffraction studies has enabled a detailed characterisation of their structure, distribution and function, opening new avenues for future diagnostic and therapeutic applications in dentistry. However, the predominance of in vitro studies highlights the need for further in vivo clinical research to confirm and translate these findings into innovative dental practices.
More Related Videos
Related Concept Videos
Patch Clamp
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Clinical Trials: Overview
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...

