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Updated: Jan 14, 2026

Author Spotlight: Cost-Effective Transcriptomic Drug Screening - Unlocking New Targets
Published on: February 23, 2024
Design and Implementation of a High-Throughput Experimentation Platform to Accelerate Drug Discovery
Amanda W Dombrowski1, Ana L Aguirre1, Ying Wang1
1AbbVie, Inc., North Chicago, Illinois 60064, United States.
Abstract:
Herein, we describe the development of the high-throughput experimentation platform and function in AbbVie's Discovery Chemistry organization. The strategy and approach tailored specifically to medicinal chemistry needs are discussed. Additionally, we disclose the top reaction conditions for the most requested transformations obtained by analysis of the combined data set generated by the platform over five years.
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