Related Experiment Video
Updated: Jan 14, 2026

Comparative Analysis of Human Growth Hormone in Serum Using SPRi, Nano-SPRi and ELISA Assays
Published on: January 7, 2016
Long-acting Growth Hormone Preparations
Kevin C J Yuen1, Margaret C S Boguszewski2
1Department of Neuroendocrinology, Barrow Pituitary Center, Barrow Neurological Institute, University of Arizona College of Medicine, Phoenix, AZ, USA; Department of Neurology, Barrow Pituitary Center, Barrow Neurological Institute, University of Arizona College of Medicine, Phoenix, AZ, USA; Creighton University School of Medicine, Phoenix, AZ, USA.
Abstract:
Once-weekly long-acting growth hormone (LAGH) preparations have demonstrated noninferiority compared to daily recombinant human growth hormone in terms of increased growth velocity and improved body composition with comparable short-term safety profiles in children with growth hormone deficiency (CGHD) and adults with growth hormone deficiency (AGHD). Currently, three LAGH preparations are approved for treatment of CGHD and one for AGHD. These agents may improve patient adherence, quality of life, and clinical outcomes. Clinicians will need to identify the best candidates for LAGH therapy and understand how to start, monitor, and adjust therapy. Long-term surveillance studies are required to demonstrate adherence, efficacy, cost-effectiveness, and safety.
More Related Videos
08:54Development of a Multicellular Three-dimensional Organotypic Model of the Human Intestinal Mucosa Grown Under Microgravity
Published on: July 25, 2016
08:24Preparation and Characterization of Novel HDL-mimicking Nanoparticles for Nerve Growth Factor Encapsulation
Published on: May 22, 2017
Related Concept Videos
Insulin Formulations: Types and Delivery
Short-acting insulins are divided into...
Glucagon-like Receptor Agonists
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by...
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Oral Hypoglycemic Agents: Glinides
Insulin: Biosynthesis, Chemistry, and Preparation
Damage or functional impairment of β-cells inhibits insulin production, leading to diabetes. Diabetes treatment...
Hormones of the Pituitary Gland
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...