[Development and future prospects of the national human biomonitoring technology system of China]

In 2025, Chinese Medical Association commemorates its 110th anniversary. Over this century-spanning journey in medical advancement, human biomonitoring (HBM) has emerged as a pivotal tool in environmental medicine for assessing population exposure to environmental pollutants and associated health risks. Since the dawn of the 21st century, China has actively advanced its HBM technological framework, providing critical scientific support for chemical regulation policies and public health protection. Chinese Journal of Preventive Medicine has consistently chronicled progress in this field, publishing high-impact research and serving as a key platform for academic exchange and knowledge dissemination.Marking this milestone, this article systematically reviews the current state of global HBM development, elucidates its indispensable role in preventive medicine, and highlights advancements and technical innovations within China's National Human Biomonitoring Program. It further examines persistent challenges and outlines future directions, offering scientific support for precision interventions in environmental health risks under the "Healthy China 2030" strategy.