Related Experiment Video
Updated: Jun 21, 2026
Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
A Pediatric Case of Hepatocellular Malignant Neoplasm, Not Otherwise Specified (HCN-NOS) With Poor Prognosis
Bin Yamaoka1, Reina Hoshi1, Kako Ono1
1Department of Pediatric Surgery, Nihon University School of Medicine, Tokyo, Japan.
Introduction:
Hepatocellular malignant neoplasm, not otherwise specified (HCN-NOS) is a newly identified liver tumor with features of mixed hepatoblastoma (HB) and hepatocellular carcinoma (HCC). Although its prognosis and treatment strategies are not well defined, some reports suggested that complete resection with HB-targeting chemotherapy may yield favorable outcomes.
Case Presentation:
We present herein a pediatric case of HCN-NOS in which the tumor was fully resected followed by postoperative chemotherapy. Unfortunately, the patient subsequently died.
Conclusion:
This case highlights the fact that hepatoblastoma protocols may not always be effective in the treatment of HCN-NOS; therefore, developing treatment strategies tailored to HCN-NOS is crucial to improve patient prognosis.
Related Concept Videos
01:24Liver Regeneration
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...
01:26Kidney Transplant II: Surgical Procedure