Comparison of Cycloplegic and Non-Cycloplegic Refraction in School-Aged Children: A Cross-Sectional, Observational

Tilottama Kar1, Ankur K Shrivastava2

  • 1Ophthalmology, All India Institute of Medical Sciences, Patna, Patna, IND.

Cureus
|October 24, 2025
PubMed

Insights

Cycloplegic refraction is crucial for accurate vision assessment in children. Non-cycloplegic methods overestimate myopia and underestimate hyperopia, highlighting the need for cycloplegic eye exams in pediatric refractive error evaluation.

Area of Science:

  • Ophthalmology
  • Pediatric Optometry
  • Refractive Error Assessment

Background:

  • Accurate refractive error assessment in children is vital for timely intervention and management of visual impairments.
  • Non-cycloplegic refraction may lead to inaccurate measurements due to accommodative effort in young individuals.

Purpose of the Study:

  • To compare cycloplegic and non-cycloplegic refraction in school-aged children.
  • To determine the impact of cycloplegia on refractive error measurements in pediatric populations.

Main Methods:

  • A cross-sectional observational study involving 110 children aged 5-15 years in central India.
  • Autorefraction was performed both with and without cycloplegia induced by cyclopentolate 1% eye drops.
  • Spherical equivalent (SE) values from the right eye were recorded for analysis.

Main Results:

  • Mean SE was -0.54 D without cycloplegia and +0.18 D with cycloplegia.
  • Non-cycloplegic refraction overestimated myopia (62.7% vs 40.9%) and underestimated hyperopia (31.8% vs 57.3%).
  • A statistically significant strong correlation was found between cycloplegic and non-cycloplegic SE values.

Conclusions:

  • Cycloplegic refraction provides a more accurate measurement of refractive errors in children compared to non-cycloplegic methods.
  • Routine use of cycloplegic refraction is recommended for precise diagnosis and management of pediatric refractive errors.
  • Understanding these differences is essential for effective myopia control and hyperopia management strategies.