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Autoimmune Polyglandular Syndrome Type 2 With Hurthle Cell Adenoma: A Rare Association
Shalini S Pandya1, Kush Shah2, Hitesh Chavda3
1Department of Internal Medicine, Sterling Hospitals, Ahmedabad, IND.
Cureus
|October 24, 2025
Summary
Autoimmune Polyglandular Syndrome type 2 (APS 2) is rare, often diagnosed late. This case highlights a unique co-occurrence with Hurthle cell adenoma, emphasizing diagnostic vigilance and management of this rare endocrinopathy.
Area of Science:
- Endocrinology
- Oncology
- Rare Diseases
Background:
- Autoimmune Polyglandular Syndrome type 2 (APS 2) is a rare endocrine disorder.
- It typically involves primary adrenal insufficiency and autoimmune thyroiditis or type 1 diabetes.
- Structural thyroid abnormalities are rarely reported in APS 2.
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