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Positive Impact of Vaccinal Status Among Notified Measles Cases in Romania in 2020-2024
Valerian-Ionuț Stoian1,2, Iulia Chiscop3, Aurora Stănescu2,4
1Medical Department, Faculty of Medicine & Pharmacy, 'Dunărea de Jos' University of Galați, 800008 Galați, Romania.
Background And Objectives:
Measles is a highly contagious but vaccine-preventable disease with significant morbidity in the European region, including Romania, especially in the post-COVID-19 era with low vaccination rates which no longer provide herd immunity. The current study aims to show how vaccination reduces the disease burden.
Methods:
A study using 29,148 cases with measles-compatible features in Romania from the 2020-2024 period was performed, analyzing symptoms, complications, and hospitalization rates comparatively between vaccinated and non-vaccinated groups.
Results:
Our findings show substantial hospitalization rates reduction among vaccinated cases with an over 12% decrease-depending on the number of MMR doses-as well as reduced severity of clinical features, but no significant effect on disease duration.
Conclusions:
MMR vaccination provides protection beyond primary disease prevention, as it reduces the disease burden among measles cases by reducing disease-related hospitalizations and improving clinical outcomes.
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