Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Facial Feedback Hypothesis01:24

Facial Feedback Hypothesis

521
Charles Darwin proposed that facial expressions are an evolutionary adaptation for communication. He argued that these expressions are not influenced by culture but are universal across species. For example, a snarling expression with exposed teeth signals a threat in many animals, including humans. Darwin also suggested that displaying an emotion can intensify the feeling. Smiling, for example, could enhance one's sense of happiness. This idea laid the foundation for understanding the role...
521
Assessment of Airway, Skin Color, and Use of Accessory Muscles01:30

Assessment of Airway, Skin Color, and Use of Accessory Muscles

1.6K
A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
1.6K
Model Approaches for Pharmacokinetic Data: Physiological Models01:15

Model Approaches for Pharmacokinetic Data: Physiological Models

232
Physiological models in pharmacokinetics are instrumental in understanding the distribution and elimination of drugs within the body. These models describe the drug concentration within target organs, influenced by factors such as drug uptake, tissue volume, and blood flow. Drug uptake is governed by the partition coefficient, which signifies the drug concentration ratio in tissue to that in the blood. The blood flow rate to a specific tissue is expressed as Qt, and the rate of change in tissue...
232

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predicting Age-Related Facial Hyperpigmentation via Dermatologist Knowledge Elicitation and Generative Modeling.

Dermatology and therapy·2026
Same author

Skin as a sentinel and modulator of systemic aging: a translational framework for evidence-based gerotherapeutics.

GeroScience·2026
Same author

Incidence and Mortality of Mucous Membrane Pemphigoid in France.

The British journal of dermatology·2026
Same author

Intelligent mirrors for longitudinal skin phenotyping.

The Journal of investigative dermatology·2026
Same author

Integrative Dermatology for Longevity: The Synergy of Topical and Internal Approaches.

Dermatology and therapy·2026
Same author

Cultural and behavioral disparities in the use of facial sun protection: a multinational analysis.

Clinical and experimental dermatology·2026
Same journal

Itch, Scratching, and Sleep Mediate the Association between Disease Severity and Quality of Life in Pruritic Dermatoses: A Cross-Sectional Study.

Dermatology and therapy·2026
Same journal

Pediatric Psoriasis: Comorbidities, Treatment Challenges and Unmet Needs.

Dermatology and therapy·2026
Same journal

Comparative Data on Long-Term Efficacy of Biologics in Moderate-to-Severe AD: An Expert Perspective on Using Indirect Comparison Methodology.

Dermatology and therapy·2026
Same journal

Comparative Effectiveness and Safety of Baricitinib and Ritlecitinib in Severe Alopecia Areata: A Real-World Monocentric Retrospective Study.

Dermatology and therapy·2026
Same journal

Matching-Adjusted Indirect Comparison of Risankizumab Versus Icotrokinra in Adult Patients with Moderate-to-Severe Plaque Psoriasis.

Dermatology and therapy·2026
Same journal

Immunobiological Therapy in Moderate-to-Severe Psoriasis: A Retrospective Cohort Study Investigating the Effects of Inadequate Therapeutic Compliance on Drug Survival.

Dermatology and therapy·2026
See all related articles

Related Experiment Video

Updated: Jan 6, 2026

Holistic Facial Composite Creation and Subsequent Video Line-up Eyewitness Identification Paradigm
09:49

Holistic Facial Composite Creation and Subsequent Video Line-up Eyewitness Identification Paradigm

Published on: December 24, 2015

14.5K

A Combined Approach to Predict Tobacco-Induced Facial Aging Using Dermatologist Knowledge Elicitation and Generative

Edouard Raynaud1,2, Laudine Bertrand3, Frederic Flament3

  • 1Bioclinical Research Center (CRB) of L'Oréal Advanced Research, Saint-Louis Hospital, Paris, France.

Dermatology and Therapy
|October 24, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a scientifically validated facial aging simulator that quantifies tobacco

Keywords:
AIArtificial intelligenceElicitationLongevityPredictive modelSkin agingSmokingTobacco

More Related Videos

Protocol for Data Collection and Analysis Applied to Automated Facial Expression Analysis Technology and Temporal Analysis for Sensory Evaluation
07:12

Protocol for Data Collection and Analysis Applied to Automated Facial Expression Analysis Technology and Temporal Analysis for Sensory Evaluation

Published on: August 26, 2016

9.8K
Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
03:47

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application

Published on: September 27, 2024

1.4K

Related Experiment Videos

Last Updated: Jan 6, 2026

Holistic Facial Composite Creation and Subsequent Video Line-up Eyewitness Identification Paradigm
09:49

Holistic Facial Composite Creation and Subsequent Video Line-up Eyewitness Identification Paradigm

Published on: December 24, 2015

14.5K
Protocol for Data Collection and Analysis Applied to Automated Facial Expression Analysis Technology and Temporal Analysis for Sensory Evaluation
07:12

Protocol for Data Collection and Analysis Applied to Automated Facial Expression Analysis Technology and Temporal Analysis for Sensory Evaluation

Published on: August 26, 2016

9.8K
Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
03:47

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application

Published on: September 27, 2024

1.4K

Area of Science:

  • Dermatology and AI-driven predictive modeling.
  • Computational aesthetics and digital image processing.
  • Public health and preventative medicine strategies.

Background:

  • Existing facial aging simulations often lack scientific rigor and transparency.
  • Personalized aging predictions, especially concerning tobacco's impact, require scientifically validated tools.
  • There is a need for reliable methods to visualize and quantify the effects of lifestyle factors on skin aging.

Purpose of the Study:

  • To develop and validate a novel facial aging simulator integrating expert knowledge and AI.
  • To predict 15-year facial aging signs and generate personalized aging simulation images.
  • To quantify the impact of cumulative tobacco consumption on specific facial aging signs.

Main Methods:

  • Combined elicited knowledge from 28 expert dermatologists with an AI image generation system.
  • Developed a machine learning model (AMGAN) trained on 600 individuals' facial aging data.
  • Predicted aging probabilities and generated simulation images, controlling for confounding variables like sun exposure and BMI.

Main Results:

  • Presented predicted probabilities of facial aging signs based on cumulative tobacco consumption.
  • Demonstrated the simulator's ability to visualize tobacco's impact on a 43-year-old subject's facial image.
  • Quantified the personalized impact of smoking (e.g., 10 vs. 20 pack-years) on specific wrinkles and pigmentation.

Conclusions:

  • The scientifically validated simulator effectively motivates lifestyle changes by visualizing smoking's aging effects.
  • Offers a personalized preventative messaging strategy, particularly for individuals resistant to traditional health advice.
  • Strengthens the scientific understanding of tobacco's specific impact on facial aging signs and skin longevity.