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Related Concept Videos

Chambers of the Heart01:16

Chambers of the Heart

The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...

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Updated: Jul 1, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Dual-Patch Technique with Ventricular Septal Defect Closure for Straddling Chordae.

Fumiya Yoneyama1, Michiaki Imamura1

  • 1Congenital Heart Surgery, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, United States.

Interdisciplinary Cardiovascular and Thoracic Surgery
|October 24, 2025
PubMed
Summary
This summary is machine-generated.

A novel dual-patch technique successfully repaired complex ventricular septal defects (VSDs) with straddling atrioventricular (AV) valve chordae. This method preserves native valve function and avoids complications in pediatric patients.

Keywords:
VSD closurecongenital heat surgerystraddling valve

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Area of Science:

  • Pediatric Cardiac Surgery
  • Congenital Heart Disease
  • Cardiovascular Surgery

Background:

  • Surgical repair of ventricular septal defects (VSDs) is complicated by straddling atrioventricular (AV) valve chordae, posing a risk to valve integrity.
  • Patients with Down syndrome often present with complex congenital heart defects, including VSDs and AV valve abnormalities.

Purpose of the Study:

  • To describe the successful application of a dual-patch technique for VSD closure in an infant with straddling AV valve chordae.
  • To evaluate the efficacy and safety of this conservative approach in preserving AV valve function and preventing conduction disturbances.

Main Methods:

  • A 5-month-old infant with Down syndrome underwent VSD closure via right atriotomy using a dual-patch technique with glutaraldehyde-treated autologous pericardial patches.
  • The patches were placed on the superior and inferior septal margins, encasing the straddling chordae without division.
  • Associated mitral and tricuspid valve clefts were repaired, and the atrial septal defect (ASD) was primarily closed.

Main Results:

  • The dual-patch technique successfully closed the large inlet VSD without residual defect.
  • Postoperative echocardiography revealed only mild AV valve regurgitation.
  • The approach preserved native valvular geometry and avoided conduction disturbances.

Conclusions:

  • The dual-patch technique provides a physiologic and conservative solution for VSD repair when straddling chordae preclude conventional methods.
  • This technique avoids chordal translocation or reimplantation, maintaining native AV valve architecture and function.
  • It represents a valuable alternative for complex congenital heart defect repair in pediatric patients.