Trends in alcohol consumption in middle-aged and older adults, assessed with self-report and the alcohol marker phosphatidylethanol - A longitudinal HUNT study
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Alcohol consumption trends show increased abstinence and decreased heavy drinking in older Norwegians since the 1990s. Risky drinking, however, is increasing with age in both sexes.
Area Of Science
- Public Health
- Epidemiology
- Alcohol Research
Background
- Alcohol consumption is a significant global health burden.
- Longitudinal alcohol consumption patterns in aging populations require examination.
Purpose Of The Study
- To analyze longitudinal trends in sex- and age-specific alcohol consumption.
- To investigate changes in drinking behaviors among middle-aged and older adults in Norway.
Main Methods
- Utilized data from the Trøndelag Health Study (HUNT) from 1995-2019.
- Included 23,151 individuals aged 43+ years across HUNT2, HUNT3, and HUNT4 surveys.
- Assessed self-reported alcohol abstinence, current drinking, risky drinking, and heavy episodic drinking, supplemented by phosphatidylethanol (PEth) biomarker data.
Main Results
- Increased alcohol abstinence and decreased heavy episodic drinking observed in both sexes from HUNT2/HUNT3 to HUNT4.
- Risky drinking increased among men and women aged 43-64 years.
- Men consistently showed higher alcohol consumption than women across most age groups.
Conclusions
- Norwegian drinking patterns have shifted towards increased abstinence and reduced heavy episodic drinking with age since the 1990s.
- A concerning trend of increasing risky drinking with age is evident in both sexes.
- Changes in men significantly influenced observed convergences in drinking patterns among older adults.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
The test of independence is a chi-square-based test used to determine whether two variables or factors are independent or dependent. This hypothesis test is used to examine the independence of the variables. One can construct two qualitative survey questions or experiments based on the variables in a contingency table. The goal is to see if the two variables are unrelated (independent) or related (dependent). The null and alternative hypotheses for this test are:
H0: The two variables (factors)...
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...