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Related Experiment Video

Updated: Jan 14, 2026

Intracranial Implantation with Subsequent 3D In Vivo Bioluminescent Imaging of Murine Gliomas
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Intracranial Implantation with Subsequent 3D In Vivo Bioluminescent Imaging of Murine Gliomas

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IV3TM: Inception V3 enabled bidirectional long short-term memory network for brain tumor classification.

Afnan M Alhassan1, Nouf I Altmami1

  • 1Department of Computer Science, College of Computing and Information Technology, Shaqra University, Shaqra, Saudi Arabia.

Plos One
|October 24, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a novel Inception V3 enabled Bidirectional Long Short Term Memory Network (IV3TM) for improved brain tumor classification using Magnetic Resonance Imaging (MRI). The IV3TM model enhances diagnostic accuracy for brain tumors.

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Area of Science:

  • Neurology
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Brain tumors are life-threatening neurological conditions requiring early diagnosis for effective treatment.
  • Deep Learning methods have advanced medical image classification but face challenges with brain tumor complexities and MRI variability.
  • Accurate brain tumor classification is crucial for patient survival rates.

Purpose of the Study:

  • To propose an advanced deep learning model, the Inception V3 enabled Bidirectional Long Short Term Memory Network (IV3TM), for brain tumor classification.
  • To enhance the performance of brain tumor classification by employing novel preprocessing and data augmentation techniques.
  • To improve the accuracy and reliability of brain tumor diagnosis from Magnetic Resonance Imaging (MRI) data.

Main Methods:

  • Implemented an iterative weighted-mean Filter for preprocessing to address bias field fluctuations, noise, and blurring in MRI images.
  • Utilized data augmentation to increase the size and diversity of the training dataset.
  • Developed the IV3TM model by integrating Inception V3 and Bidirectional Long Short Term Memory (BiLSTM) to capture sequential dependencies in MRI data, using SqueezeNet for image segmentation.

Main Results:

  • The proposed IV3TM model demonstrated effectiveness in brain tumor classification.
  • Evaluated performance using metrics such as specificity, accuracy, precision, F1-score, and sensitivity.
  • Assessed model error using root mean square error (RMSE), showing encouraging results on Brain MRI and Figshare datasets.

Conclusions:

  • The IV3TM model offers a promising approach for accurate brain tumor classification from MRI scans.
  • The integration of Inception V3 and BiLSTM effectively learns intricate structural relationships in brain MRI data.
  • The proposed method shows potential for aiding neurologists in timely and precise brain tumor diagnosis.