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Related Concept Videos

Blinding01:11

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

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The Web-Based Recognise and Respond Gatekeeper Training Program: Noninferiority Randomized Trial.

Cassandra Chakouch1, Ann M Martin1, Philip J Batterham2

  • 1Black Dog Institute, University of New South Wales, Hospital Road, Randwick, Sydney, 2031, Australia, 61 412454898.

JMIR Mental Health
|October 24, 2025
PubMed
Summary
This summary is machine-generated.

The Recognise and Respond (R&R) online program is as effective as the Question, Persuade, Refer (QPR) program in boosting gatekeeper confidence for suicide prevention. Both programs improved confidence, attitudes, and knowledge in identifying and supporting individuals with suicidal thoughts.

Keywords:
AustralianRCTRecognise and Responddepressiongatekeeper trainingmental healthnoninferioritynoninferiority trialonline interventionrandomized controlled trialsuicidesuicide preventionweb-based

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Area of Science:

  • Psychology
  • Public Health
  • Online Education

Background:

  • Gatekeeper training equips community members to identify and support individuals at risk of suicide.
  • The Recognise and Respond (R&R) program is a new online intervention tailored for the Australian context, developed with expert and lived experience input.
  • Existing gatekeeper training programs require context-specific adaptations and evaluations.

Purpose of the Study:

  • To evaluate the noninferiority of the R&R online program compared to the established QPR online program in enhancing gatekeeper confidence.
  • To assess the short- and medium-term effects of R&R on attitudes toward suicide prevention and knowledge of appropriate responses.
  • To provide an evidence-based online gatekeeper training option for the Australian population.

Main Methods:

  • A randomized controlled trial involving 524 participants comparing R&R to QPR.
  • Primary outcome: gatekeeper confidence assessed via a noninferiority framework.
  • Secondary outcomes: attitudes and knowledge assessed via superiority testing, with data collected at baseline, post-intervention, and 3-month follow-up.

Main Results:

  • Both R&R and QPR significantly improved gatekeeper confidence, demonstrating noninferiority of R&R.
  • Significant improvements in attitudes and knowledge were observed in both groups post-intervention and at follow-up.
  • While QPR showed greater initial improvement in attitude scores, gains were maintained at follow-up for both programs without other significant between-group differences.

Conclusions:

  • The R&R online program is effective and noninferior to QPR in improving gatekeeper confidence for suicide prevention.
  • R&R provides a viable online training solution for enhancing community capacity in suicide intervention.
  • Findings support the use of R&R for widespread implementation in suicide prevention efforts.