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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Heart Valves01:16

Heart Valves

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The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
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Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

453
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
453
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

374
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
374
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

409
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
409
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

274
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
274

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Related Experiment Video

Updated: Jan 14, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
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Beating-Heart Pulmonary Valve Replacement for Isolated Monocuspid Valve.

Mohammad Abbasi1, Abdul Rahman Alizada2, Navid Abbasiyan Fallahi3

  • 1Mashhad University of Medical Sciences, Mashhad, Iran.

JACC. Case Reports
|October 24, 2025
PubMed
Summary

Isolated monocuspid pulmonary valve, though rare, can cause severe heart issues. Beating-heart pulmonary valve replacement (PVR) offers a less invasive surgical option for these complex congenital heart defects.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Congenital Heart Disease

Background:

  • Monocuspid pulmonary valve is a rare congenital anomaly, often associated with other heart defects.
Keywords:
cardioplegiacardiopulmonary bypasscase reportcongenital heart defectspulmonary artery aneurysmright ventricular dilation

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  • Isolated monocuspid pulmonary valve is exceptionally uncommon.
  • This condition can lead to progressive pulmonary valve insufficiency and pulmonary artery aneurysm.