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Fatal case of obstructive fibrinous tracheal pseudomembrane caused by hemorrhagic tracheal rupture during

Xin Zhao1,2, Zhiming Chen3,4, Bo Wang2,5

  • 1State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, 130062, China.

International Journal of Legal Medicine
|October 24, 2025
PubMed

Insights

Obstructive fibrinous tracheal pseudomembrane (OFTP) is a rare airway obstruction. This case highlights OFTP

Area of Science:

  • Forensic Pathology
  • Pulmonology
  • Medical Imaging

Background:

  • Obstructive fibrinous tracheal pseudomembrane (OFTP) is a rare, life-threatening airway condition.
  • OFTP formation can lead to airway occlusion due to fibrin-rich membranes.

Purpose of the Study:

  • To report a fatal case of OFTP.
  • To emphasize the diagnostic challenges and forensic value of post-mortem imaging in OFTP.

Main Methods:

  • Case report of a 16-year-old female with fatal OFTP.
  • Diagnosis confirmed via post-mortem magnetic resonance imaging (PMMR), post-mortem computed tomography (PMCT), and autopsy.
  • Procedure involved rigid bronchoscopy.

Main Results:

  • The patient experienced massive hemorrhage and tracheal rupture during bronchoscopy.
  • Death occurred due to asphyxia secondary to OFTP complications.
  • Multimodal post-mortem imaging confirmed OFTP and associated trauma.

Conclusions:

  • OFTP should be considered in patients with airway issues post-intubation.
  • Multimodal post-mortem imaging is crucial for diagnosing OFTP and its complications.
  • This case highlights the importance of recognizing OFTP during bronchoscopy, especially after endotracheal intubation.
Keywords:
BronchoscopyEndotracheal intubationObstructive fibrinous tracheal pseudomembranePost-mortem computed tomographyPost-mortem magnetic resonance imaging

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