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Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies
Published on: October 6, 2022
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Laparoscopic excision of the sciatic nerve endometriosis
Mario Ćorić1, Anita Jug Klobučić2
1Department of Gynecological Surgery, Endometriosis Referral Center, University Clinical Hospital Center, Zagreb, Croatia. mcoric77@gmail.com.
Archives of Gynecology and Obstetrics
|October 25, 2025
Summary
A forty-year-old patient experienced persistent sciatic pain despite treatment for adenomyosis and metrorrhagia with a hormonal intrauterine device. Magnetic resonance imaging confirmed an endometriotic nodule compressing the sciatic nerve, successfully treated with laparoscopic surgery.
Area of Science:
- Gynecology
- Neurology
- Surgical Science
Background:
- Adenomyosis and metrorrhagia are common gynecological conditions.
- Sciatic pain can be a debilitating symptom during menstruation.
- Hormonal treatments like the levonorgestrel-releasing intrauterine device (LNG-IUD) are often used for heavy bleeding.

