A unique imaging sign: tiny cysts across the brain and spine

Diffuse Leptomeningeal Glioneuronal Tumor (DLGNT) is a rare neoplasm in children with variable clinical and radiological features, often leading to diagnostic delays.We present the case of a 3-year-old boy with tonic-clonic seizures and gait disturbance. Brain and spine MRI revealed widespread, non-enhancing, cystic lesions along the cerebral sulci and subarachnoid space. Biopsy confirmed the diagnosis of DLGNT. This case demonstrates a unique radiological presentation of DLGNT as diffuse, non-enhancing cystic lesions. Recognizing this unique imaging pattern is crucial for early diagnosis, especially in pediatric patients.