Visual performance of a non-diffractive extended depth of focus intraocular lens

This study aimed to evaluate the monocular and binocular visual performance of a new non-diffractive extended depth of focus (EDoF) intraocular lens (IOL).

In this prospective, non-randomized, single-arm, single-center, open-label study, the eyes of consecutive patients who received bilateral implantation of a non-diffractive EDoF IOL (Acrysof IQ Vivity, Alcon Laboratories) were evaluated. Monocular and binocular best corrected and uncorrected distance, intermediate, and near visual acuity (VA), as well as monocular defocus curve and contrast sensitivity, were assessed.

Seventy-six eyes of 38 patients were included. The mean subjective spherical equivalent was -0.13. Binocular distance-corrected VA was -0.16 LogMAR at 6 meters, 0.12 LogMAR at 66 centimeters, and 0.35 LogMAR at 40 centimeters. Monocular distance-corrected VA was -0.10 LogMAR, 0.20 LogMAR, and 0.45 LogMAR at the same respective distances. Uncorrected VA at distance, intermediate, and near were -0.08 LogMAR, 0.14 LogMAR, and 0.33 LogMAR for binocular vision, and 0.00 LogMAR, 0.20 LogMAR, and 0.43 LogMAR for monocular vision. The monocular defocus curve was below 0.08 LogMAR up to -1.5 D defocus and below 0.25 LogMAR up to -2.0 D defocus. Average monocular contrast sensitivity peaked at 3.00 cycles/degree at 0.92 log units, decreasing at higher spatial frequencies. Most patients reported no visual disturbances post-implantation; 8% reported ghosting, and 5% reported glare.

This non-diffractive extended depth of focus intraocular lens provides good visual acuity and quality at far and intermediate distances, functional near vision, and high spectacle-independent outcomes with minimal visual disturbances.