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Updated: Jan 14, 2026

Author Spotlight: Point-of-Care Ultrasound for Gastric Content Assessment and Risk Stratification in Perioperative Care
Published on: September 22, 2023
Abdominal manifestations of Q fever
Eva Špitalská1, Peter Sabaka2, Andrea Komorníková3
1Biomedical Research Center, Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovakia; National Reference Centre for Surveillance and Laboratory diagnosis of Rickettsioses Banská Bystrica, Performance workplace Institute of Virology, Bratislava, Slovakia.
Objectives:
Hepatopathy of the steatosis type, splenopathy, and a hypoechoic enlarged gallbladder on abdominal ultrasonography are indications of sudden inflammation affecting the abdominal region. Such a clinical picture due to Q fever is common. However, infectious etiologies for primary mesenteric adenitis are rare.
Methods:
A complete biochemistry and clinical examination of the patients, followed by a spectrum of serological and molecular biological tests were performed to detect a causative agent of a very serious, highly infectious illness.
Results:
Here we report two exceptional cases of Q fever. Physical examination at the time of hospitalization revealed malaise, which was primarily manifested by temperature >38°C. Both patients presented overlapping clinical and laboratory parameters, an elevated lymphocyte, and liver enzyme levels, and high C-reactive protein. The diagnosis of "query" hepatopathy, enlarged gallbladder, splenomegaly and newly, mesenteric adenitis was confirmed by computed tomography scan of the abdomen and pelvis. Serological examination and molecular detection of the pathogen confirmed Coxiella burnetii as the causative agent.
Conclusions:
We recommend Q fever be considered not only in cases of acute hepatopathy, enlarged gallbladder and spleen, but also on the occurrence of mesenteric adenitis.
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