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In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
Published on: May 24, 2020
Organ-on-chip technologies at the cancer-thrombosis interface
Inês Soares Marques1, Raquel Almeida2, Pedro F Costa3
1BIOFABICS - 3D Biotissue Analogues, Porto, Portugal; Institute for Research and Innovation in Health (i3S), University of Porto, Porto, Portugal; School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal.
None:
Cancer-associated thrombosis (CAT) is the second leading cause of death among cancer patients, driven by tumour-haemostasis interactions. While traditional models have proven invaluable to study this process, they often fail to replicate its complexity. Organ-on-chip (OoC) offers a promising alternative, potentially enhancing understanding of CAT mechanisms and advancing therapeutic strategies.

