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Cutaneous Talaromyces marneffei Infection in an Immunocompetent Adolescent: A Case Report
Yue Chen1, Xiaodong Li1, Chao Bi1
1Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, Guangdong, People's Republic of China.
Clinical, Cosmetic and Investigational Dermatology
|October 27, 2025
Summary
Talaromyces marneffei (TM) infection, a deep fungal disease, can affect immunocompetent individuals. Metagenomic sequencing aided diagnosis in a young girl with skin lesions, leading to successful treatment with itraconazole.
Area of Science:
- Mycology
- Infectious Diseases
- Dermatology
Background:
- Talaromyces marneffei (TM) infection is a serious fungal disease primarily affecting immunocompromised individuals in endemic areas.
- An emerging trend shows TM infections in HIV-negative, immunocompetent patients, challenging traditional diagnostic assumptions.
- Chronic granulomatous skin lesions and lymphadenopathy can mimic other conditions like tuberculosis.
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