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Updated: Jan 14, 2026

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Published on: August 30, 2020
Neurogenic Stunned Myocardium: A Narrative Review of Cardiopulmonary Failure Related to Subarachnoidal Haemorrhage
Dharmanand Ramnarain1, Susan Deenen2, Laura Boerboom3
1Intensive Care Medicine, Elisabeth-Tweesteden Hospital, Tilburg, NLD.
Acute subarachnoid haemorrhage (SAH) is an acute bleeding in the subarachnoid space in the brain. Due to various pathophysiological sequelae, SAH can be accompanied by acute cardiac failure. Patients who suffer from cardiac failure due to SAH have a high morbidity and mortality. Although the pathophysiology is not completely understood in both clinical and experimental studies, several attempts have been made and published to explain the pathophysiological mechanisms of cardiac failure in SAH patients. Two forms of cardiac failure are described after neurologic injury (like SAH) which are neurogenic stunned myocardium (NSM) with or without diffuse and/or regional wall motion abnormalities (RWMA), and a more specific form called takotsubo cardiomyopathy. This review aims to summarise the current literature on cardiac abnormalities and related pathophysiology in patients with SAH.
Acute subarachnoid haemorrhage (SAH) is an acute bleeding in the subarachnoid space in the brain. Due to various pathophysiological sequelae, SAH can be accompanied by acute cardiac failure. Patients who suffer from cardiac failure due to SAH have a high morbidity and mortality. Although the pathophysiology is not completely understood in both clinical and experimental studies, several attempts have been made and published to explain the pathophysiological mechanisms of cardiac failure in SAH patients. Two forms of cardiac failure are described after neurologic injury (like SAH) which are neurogenic stunned myocardium (NSM) with or without diffuse and/or regional wall motion abnormalities (RWMA), and a more specific form called takotsubo cardiomyopathy. This review aims to summarise the current literature on cardiac abnormalities and related pathophysiology in patients with SAH.
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