Laryngeal mask versus intubation on adverse reactions in pediatric retinoblastoma patients

Fei Huo1, Hansheng Liang1, Lan Gao1

  • 1Department of Anesthesiology, Peking University People's Hospital, Beijing, China.

Translational Pediatrics
|October 27, 2025
PubMed

Insights

Laryngeal mask airway (LMA) use in pediatric eye enucleation surgery offers more stable conditions and comparable safety to endotracheal intubation (ETT). This study suggests LMA is a viable airway management option for these young patients.

Area of Science:

  • Pediatric Anesthesiology
  • Ophthalmologic Surgery
  • Airway Management

Background:

  • Enucleation surgery in children, often for retinoblastoma, necessitates general anesthesia and airway management.
  • Laryngeal mask airway (LMA) and endotracheal intubation (ETT) are common pediatric anesthesia techniques.
  • Comparative efficacy and safety data for LMA versus ETT in pediatric enucleation surgery are limited.

Purpose of the Study:

  • To compare the efficacy and safety of LMA versus ETT in children undergoing enucleation surgery.
  • To evaluate hemodynamic stability and perioperative complications associated with each airway management technique.

Main Methods:

  • Retrospective review of 58 pediatric patients undergoing enucleation surgery (2007-2020).
  • Patients were divided into two groups: Group A (endotracheal intubation, n=35) and Group B (laryngeal mask airway, n=23).
  • Analysis included demographic data, heart rate (HR), mean arterial pressure (MAP), and perioperative complications.

Main Results:

  • Laryngeal mask airway (LMA) was used in 39.66% of patients.
  • Group B (LMA) showed significantly lower heart rate before skin incision compared to Group A (ETT) (P=0.02).
  • One patient in Group B experienced laryngeal spasm, and another required a second LMA insertion attempt.

Conclusions:

  • Laryngeal mask airway (LMA) intubation provides more stable perioperative conditions for pediatric enucleation surgery.
  • LMA intubation demonstrated comparable safety to endotracheal intubation (ETT), with no increase in adverse events.
Abstract

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