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Case Report: Late Hypersensitivity Reaction to Hydroxyurea in a Patient With Myeloproliferative Disorder

Navkirat Kahlon1, Sujatha Baddam2, Harinderjeet Kaur3

  • 1Department of Medical Oncology, Mass General Cancer Center at Wentworth-Douglass Hospital, Dover, New Hampshire, USA.

Case Reports in Hematology
|October 27, 2025
PubMed
Summary

Hydroxyurea, a key treatment for myelofibrosis, can cause rare hypersensitivity reactions. This case shows that discontinuing hydroxyurea and switching to ruxolitinib resolved symptoms, highlighting the need for careful management.

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