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Updated: Jan 14, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Two attempts at transcatheter device closure of an acquired Gerbode defect following mitral valve replacement: a case
Thi Minh Ly Nguyen1,2, Hieu L Nguyen1,2, Viet L Nguyen1,2
1Department of Cardiology, Hanoi Medical University, 1 Ton That Tung, Dong Da, Ha Noi 100000, Viet Nam.
Background:
A Gerbode defect, an abnormal communication between the left ventricle and right atrium, is acquired or congenital. A significant Gerbode defect may lead to symptomatic heart failure, requiring closure through surgery or intervention.
Case Summary:
We present a case of an acquired Gerbode defect in a 47-year-old woman with rheumatic heart disease who underwent a second mitral valve replacement. Postoperatively, heart failure was observed, which was attributed to severe tricuspid valve regurgitation. Subsequently, transthoracic and transoesophageal echocardiography and cardiac magnetic resonance imaging were used to establish a definitive diagnosis. The patient was successfully treated with percutaneous device closure, resulting in complete resolution of her heart failure.
Discussion:
Gerbode defects can occur following cardiac surgery and are frequently misdiagnosed as tricuspid regurgitation or pulmonary hypertension. Transcatheter device closure may be a viable treatment option for patients at high risk of reoperation. However, it should be performed at a specialized centre with expertise in cardiac intervention.
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