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RESCUER mobile app to support pediatric resuscitation: Study protocol for a randomized controlled trial

Samantha A Lee1,2, Diego Trujillo1,2, Garth D Meckler3

  • 1Department of Obstetrics & Gynecology, Beth Israel Deaconess Medical Centre, Boston, MA, USA.

Contemporary Clinical Trials Communications
|October 27, 2025
PubMed

Insights

A new app, RESCUER, aims to improve pediatric cardiac arrest response times for Emergency Medical Services (EMS) clinicians. This study will test if the app enhances resuscitation performance and reduces cognitive load during simulated pediatric out-of-hospital cardiac arrests (POHCA).

Area of Science:

  • Emergency medicine
  • Pediatric resuscitation
  • Health informatics

Background:

  • Pediatric out-of-hospital cardiac arrest (POHCA) is a significant cause of child mortality.
  • Current Emergency Medical Services (EMS) protocols guide response to POHCA.
  • There is a need for tools to support EMS clinicians during these critical events.

Purpose of the Study:

  • To evaluate the effectiveness of the RESCUER cognitive aid app in supporting EMS clinicians during simulated neonatal and POHCA.
  • To compare the RESCUER app's impact on resuscitation performance against standard EMS care.
  • To assess the app's influence on cognitive load and usability in a simulated POHCA setting.

Main Methods:

  • A randomized controlled trial (RCT) involving EMS first responders from rural and urban US agencies.
  • EMS teams will be randomized to use either the RESCUER app or their current standard of care during simulated POHCAs.
  • The order of simulation scenarios will also be randomized.

Main Results:

  • Primary outcomes include time to complete American Heart Association (AHA)-recommended steps for Neonatal Resuscitation Program (NRP) and Pediatric Advanced Life Support (PALS).
  • Secondary outcomes encompass participants' self-rated cognitive load, teamwork effectiveness, and tool usability.
  • Hypothesis: The RESCUER app will decrease time to complete AHA steps compared to standard care.

Conclusions:

  • The study hypothesizes that the RESCUER app will improve resuscitation performance in simulated POHCAs.
  • The app is expected to reduce the time required to complete critical resuscitation steps.
  • This research aims to determine if the RESCUER app can enhance EMS response to pediatric emergencies.
Abstract

Keywords:
Cardiopulmonary resuscitationEmergency medical servicesMobile applicationsPatient safetyPediatricsRandomized controlled trial (RCT)

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