Functions of wheat ncRNAs in pathogen defense and stress adaptation
Yongji Yang1, Yi Hu1, Tao Li1
1Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Zhongshan Biological Breeding Laboratory/Key Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genetics and Physiology, Agricultural College of Yangzhou University, Yangzhou, China.
Abstract:
In organisms, non-coding RNAs (ncRNAs) are key regulatory elements that modulate, the expression of genes involved in diverse biological traits. Among them, micro RNAs (miRNAs), small interfering RNAs (siRNAs), and long non-coding RNAs (lncRNAs) have become major research focuses. Wheat, the world's most widely grown crop, occupies 17% of global cultivated land and supplies ∼55% of the world's carbohydrates. Understanding the roles, identification, and mechanisms of wheat ncRNAs is essential for both basic research and crop improvement. Through systematic searches of PubMed, Web of Science, and EndNote databases, this study identified 182 publications related to wheat ncRNAs. Based on predefined criteria-research relevance and publication timeframe (2015-2025)-70 high-quality studies were selected for in-depth analysis. This review comprehensively summarizes recent advances in ncRNA research (focusing on lncRNAs and small RNAs) in relation to wheat diseases, pests, and responses to biotic and abiotic stress. By integrating traditional classification with functional characterization, we developed a comprehensive analytical framework encompassing "molecular characteristics-biotic stress-abiotic stress". Furthermore, this review consolidates multi-omics high-throughput data and online ncRNA databases. The integration of multi-omics technologies aims to provide both a theoretical foundation and novel strategies for wheat genetic improvement.
Related Concept Videos
Other Stress Responses in Bacteria
Defenses Against Pathogens and Herbivores
CRISPR and crRNAs
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
Translational Regulation
Responses to Heat and Cold Stress
Types of RNA
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...


