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Updated: Jan 14, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Pleural connection treated with stent plus endobronchial valve.
Mayank Goyal1, Ashwariya Ohri1, Preeyati Chopra1
1Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
A novel endoscopic technique using a one-way valve within a stent successfully treated a refractory esophago-pleural fistula (EPF) in a non-surgical patient. This minimally invasive approach offers a promising solution for complex EPF cases.
Area of Science:
- Gastroenterology
- Thoracic Surgery
- Interventional Endoscopy
Background:
- Esophago-pleural fistula (EPF) is a rare, severe condition with high morbidity and mortality.
- Surgical repair is standard but not feasible for all patients.
- Previous endoscopic treatments for chronic EPF have shown limited success.
Purpose of the Study:
- To describe a novel endoscopic and bronchoscopic management strategy for a refractory esophago-pleural fistula in a non-surgical candidate.
Main Methods:
- A patient with refractory EPF after sleeve gastrectomy and Roux-en-Y esophagojejunostomy was treated.
- Initial management involved an endobronchial valve within a biliary metal stent.
- A fully covered biliary stent with a deployed endobronchial valve was used for fistula closure.
Main Results:
- The combined stent and valve technique facilitated gradual decompression of the abscess cavity.
- Imaging at 6 months confirmed complete resolution of the esophago-pleural fistula.
- The stent and valve were successfully removed after fistula closure.
Conclusions:
- Endoscopic and bronchoscopic management is a viable alternative for non-surgical candidates with EPF.
- This novel technique of deploying a valve within a stent is a promising minimally invasive solution for refractory EPF.
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