Challenges to overcome obstacles for pediatric donor heart availability

Norihide Fukushima1

  • 1Senri Kinran University, 5-25-1 Fujishiro-dai, Suita, Osaka, 565-0873, Japan.

JHLT Open
|October 27, 2025
PubMed

Insights

Pediatric heart transplantation is crucial for complex congenital heart disease (CHD). This review examines the persistent challenges limiting the availability of donor hearts for children needing this life-saving procedure.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Surgery
  • Transplantation Medicine

Background:

  • Surgical techniques for congenital heart disease (CHD) have advanced.
  • Pediatric heart transplantation is the primary treatment for severe pediatric heart failure due to complex CHD or cardiomyopathy.
  • Limited donor heart availability poses a significant challenge in pediatric transplantation.

Purpose of the Study:

  • To review the historical and current obstacles to increasing the availability of donor hearts for pediatric heart transplantation.
  • To identify key challenges hindering the pediatric donor pool.

Main Methods:

  • Literature review of past and current research on pediatric donor heart availability.
  • Analysis of factors affecting donor organ procurement and allocation for pediatric recipients.

Main Results:

  • Despite surgical advancements, donor heart scarcity remains a critical issue for children with end-stage heart failure.
  • Several factors contribute to the limited availability of pediatric donor hearts, including organ size matching and ethical considerations.

Conclusions:

  • Overcoming the shortage of pediatric donor hearts requires addressing multifaceted challenges.
  • Innovative strategies and policy changes are needed to improve donor heart availability for pediatric heart transplantation.

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