Related Experiment Video
Updated: Jan 14, 2026

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
[Endocardial left ventricular pacing in 2025]
Martin Seifert1, Christian Georgi2, Paulina Jankowska2
1Abteilung für Kardiologie, Immanuel Klinikum Bernau und Herzzentrum Brandenburg - Universitätsklinikum der Medizinischen Hochschule Brandenburg Theodor Fontane, Ladeburger Straße 17, 16321, Bernau bei Berlin, Deutschland. martin.seifert@mhb-fontane.de.
Abstract:
Cardiac resynchronization therapy (CRT) has gained a new partner in the treatment of systolic heart failure with the possibility of lead system stimulation. In parallel, leadless systems for right ventricular stimulation are being used, particularly in cases of venous access problems, infections, or other complications associated with leads. Endocardial, leadless left ventricular stimulation has been in clinical use for over 10 years now and is continuously being developed. It offers the alternative of stimulating the left ventricle endocardially and leadlessly via a co-implant, either posterolateral-basal or at the left (Tawara) branch of the left ventricular endocardium. This article presents the development, previous challenges, and new approaches to the implantation of the WiSE-CRT system (wireless stimulation endocardially). In addition, the clinical data situation and current approvals will be discussed.
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