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RASSF1A and its epigenetic dysregulation in genitourinary cancer: a current update

Sandeep Appunni1,2, Vivek Anand1,3, Madhuram Khandelwal1,4

  • 1Department of Biochemistry, All India Institute of Medical Sciences, Room No. 3015, New Delhi, India.

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
|October 27, 2025
PubMed
Summary

The tumor suppressor RASSF1A is frequently silenced by hypermethylation in genitourinary cancers. Evaluating RASSF1A methylation aids diagnosis and suggests novel therapeutic strategies for improved patient outcomes.

Keywords:
Bladder cancerGenitourinary cancerProstate cancerRASSF1ATumor suppressor genes

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