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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
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Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
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Herpes simplex virus ileitis.

Zoya Hasan1, Meeta Singh2, Ank Vaish3

  • 1Senior Resident, Department of Pathology, Maulana Azad Medical College, New Delhi, India.

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|October 27, 2025
PubMed
Summary
This summary is machine-generated.

Herpes simplex virus (HSV) ileal infection is rare in immunocompromised patients. This case highlights a dual infection of HSV-1 and tubercular ileitis, emphasizing the need for thorough diagnosis in complex gastrointestinal presentations.

Keywords:
Tuberculosispublic healthviral infection

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Virology

Background:

  • Herpes simplex virus (HSV) gastrointestinal infections are uncommon, primarily affecting the esophagus in immunocompromised individuals.
  • HSV colitis can occur, particularly in inflammatory bowel disease patients on immunosuppressive therapy.
  • Small intestine involvement by HSV is exceptionally rare.

Purpose of the Study:

  • To report an extremely rare case of dual ileal infection involving Herpes simplex virus type 1 (HSV-1) and tuberculosis.
  • To highlight the diagnostic challenges and clinical implications of concurrent gastrointestinal infections in immunocompromised hosts.

Main Methods:

  • Case report of a 30-year-old immunocompromised individual.
  • Clinical presentation, diagnostic investigations, and treatment of dual ileal infection.

Main Results:

  • The patient presented with a rare dual ileal infection: HSV-1 and tubercular ileitis.
  • This dual infection underscores the potential for unusual gastrointestinal manifestations in immunocompromised individuals.

Conclusions:

  • Dual ileal infections, such as HSV-1 and tuberculosis, are exceedingly rare but possible in immunocompromised patients.
  • This case emphasizes the importance of considering a broad differential diagnosis for gastrointestinal symptoms in this population.