Related Experiment Video

Updated: Jan 13, 2026

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
08:45

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors

Published on: July 17, 2020

6.6K

Targeting PP2A in cancer: an underrated option

Fabio Sarais1, Finja Krempien1, Caroline Koehn2

  • 1Institute of Clinical Chemistry and Laboratory Medicine, Rostock University Medical Center, Rostock, Germany.

Journal of Experimental & Clinical Cancer Research : CR
|October 28, 2025
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
10:27

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

7.8K
Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

17.0K

Related Experiment Videos

Last Updated: Jan 13, 2026

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
08:45

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors

Published on: July 17, 2020

6.6K
Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
10:27

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

7.8K
Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

17.0K

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

8.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.6K
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

5.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.9K

Articles linked to this work by shared authors, journal, and citation graph.

Determining Preparation-Induced Differences in Local Forces Acting along Polymer Chains in Spin-Coated Films.

ACS macro letters·2026

Functional and behavioral outcomes in pediatric adrenal carcinoma under mitotane therapy: a caregiver-reported pilot study.

Endocrine oncology (Bristol, England)·2026

Emergency reversal of Rivaroxaban with Andexanet alfa in a child with hemorrhagic brain metastasis from Wilms tumor.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026

miRNA profiling in pediatric and young adult Burkitt leukemia and lymphoma.

Virchows Archiv : an international journal of pathology·2026

Mitotane dosage, plasma levels, and anthropometric measurements in pediatric adrenocortical carcinoma.

Endocrine oncology (Bristol, England)·2026

Deep mantle clues to Earth's watery beginning.

Science (New York, N.Y.)·2025

Beyond DNA damage: 3D tumor models and the integrin mechanobiology of radioresistance.

Journal of experimental & clinical cancer research : CR·2026

Tailored FcγR blockade enhances immune checkpoint therapy and overcomes resistance.

Journal of experimental & clinical cancer research : CR·2026

Transcriptional evidence of neuroendocrine cell plasticity beyond histological boundaries in lung neuroendocrine neoplasms: an in-silico analysis suggesting a progression model.

Journal of experimental & clinical cancer research : CR·2026

Soulangianolide A targets FAM120A to disrupt SREBP1-driven lipid metabolic reprogramming and suppress clear cell renal cell carcinoma.

Journal of experimental & clinical cancer research : CR·2026

TWIST1 bridges p53 and MDM2 and impairs the efficacy of MDM2 inhibitors.

Journal of experimental & clinical cancer research : CR·2026

Circulating NSUN6 serves as a prognostic biomarker for early metastasis in HCC via hippo pathway modulation.

Journal of experimental & clinical cancer research : CR·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us