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Dynamic Contrast-Enhanced MRI in the Evaluation of Soft Tissue Tumors and Tumor-Like Lesions: Technical Principles
In Sook Lee1,2, You Seon Song1,3, Young Jin Choi3,4
1Department of Radiology, Pusan National University Hospital, Biomedical Research Institute, Busan, Republic of Korea.
Abstract:
Dynamic contrast-enhanced (DCE) MRI is an advanced imaging technique that involves intravenous administration of a contrast agent followed by serial imaging to characterize temporal enhancement patterns. This technique provides essential information on tissue vascularity, perfusion, and capillary permeability, which are essential for characterizing soft tissue lesions. DCE-MRI plays a valuable role in differentiating benign from malignant lesions, distinguishing neoplastic from non-neoplastic conditions, evaluating histological grades, and monitoring post-treatment changes by enabling both qualitative and quantitative assessments of tissue enhancement dynamics. This review provides a comprehensive overview of the technical principles of DCE-MRI, summarizes current analytical approaches, and discusses its clinical applications in the evaluation of soft tissue tumors and tumor-like lesions.
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