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Prevalence of Cardiovascular Risk Factors in Smokers Versus Non-smokers: A Cross-Sectional Analysis
Junaid Ayaz Khan1, Waniza Ali2, Shalika Gunasekaran3
1Internal Medicine, Sun Yat-sen Medical College, Guangzhou, CHN.
Insights
Smoking significantly increases cardiovascular risk in Pakistan. Smokers exhibit higher cardiovascular risk scores compared to non-smokers, highlighting the urgent need for smoking cessation interventions.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Cardiovascular disease (CVD) is a leading global cause of mortality.
- Smoking is a primary risk factor for CVD development.
- Pakistan has high smoking rates, necessitating research into associated cardiovascular risks.
Purpose of the Study:
- To compare cardiovascular risk between smokers and non-smokers in Pakistan.
- To investigate the relationship between smoking habits and cardiovascular risk factors.
- To address a gap in cardiovascular health research within the Pakistani population.
Main Methods:
- A cross-sectional study involving 300 participants in Sialkot, Pakistan.
- Data collected via self-administered questionnaires on demographics, smoking status, and cardiovascular health.
- Cardiovascular risk assessed using the INTERHEART Modifiable Risk Score (IHMRS).
Main Results:
- Smokers (63%) had significantly higher IHMRS scores (29.95 ± 3.10) than non-smokers (37%) (26.85 ± 2.90).
- Cardiovascular risk factors correlated with smoking intensity (cigarettes/day) and duration.
- History of CVD and family history of CVD were linked to smoking intensity and duration.
Conclusions:
- Smoking is a significant contributor to elevated cardiovascular risk in Pakistan.
- Smokers face substantially higher cardiovascular risks than non-smokers.
- Public health initiatives, including smoking cessation programs, are crucial for reducing CVD burden.
Abstract:
Background Cardiovascular disease (CVD) is one of the significant causes of death worldwide, and smoking is a major causative factor of CVD pathogenesis. Smoking rates are high in Pakistan, and the related cardiovascular risks are concerning. The purpose of this study is to compare cardiovascular risk between smokers and non-smokers in a Pakistani population, addressing an under-researched context in cardiovascular health. Methods A cross-sectional study was conducted at hospitals in Sialkot from March to July 2025. Participants: A total of 300 participants were included, using convenience sampling. Demographic, smoking status, and cardiovascular health data were obtained using a self-administered questionnaire. The INTERHEART Modifiable Risk Score (IHMRS) was employed to report cardiovascular risk. Data were analyzed using SPSS v.26, employing descriptive statistics, correlation analysis, and multiple regression models. Results Of the sample, 190 (63%) were smokers and 110 (37%) were non-smokers. IHMRS scores were significantly higher (29.95 ± 3.10) in smokers than in non-smokers (26.85 ± 2.90) (p<0.001). The cardiovascular risk factors were closely linked to the number of cigarettes smoked per day and to the duration of smoking. The history of cardiovascular disease and family history of CVD were positively correlated with smoking intensity and duration (p<0.001). Conclusion Smoking significantly contributes to an increase in cardiovascular risk in Pakistan, and the cardiovascular risks of smokers are higher. The findings highlight the importance of specific population health measures, such as smoking cessation programs, to lessen the burden of cardiovascular diseases in the population.
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