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Effect of Camel Milk on the Spirometry Parameters of Children With Cystic Fibrosis: The First Double Blind Randomized
Seyed Javad Sayedi1, Toktam Kheirabadi1, Saeid Zibaee2
1Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Insights
Camel milk significantly improved respiratory function in children with cystic fibrosis (CF). This randomized trial showed enhanced spirometry parameters after daily camel milk consumption, with no adverse effects observed.
Area of Science:
- Pediatric Pulmonology
- Nutritional Science
- Clinical Trials
Background:
- Cystic Fibrosis (CF) is a genetic disorder primarily affecting children's respiratory systems.
- Camel milk has shown potential benefits for respiratory health, warranting investigation in CF patients.
Purpose of the Study:
- To evaluate the impact of camel milk consumption on spirometry parameters in pediatric CF patients.
- To assess changes in respiratory function following a 2-month intervention with camel milk.
Main Methods:
- A randomized, double-blind clinical trial involving 60 children with CF (age > 6 years).
- Participants received 300 ml of camel milk or cow milk (placebo) daily for 2 months.
- Spirometry (FEV1, FVC, FEV1/FVC) and medication use were assessed pre- and post-intervention.
Main Results:
- Camel milk consumption led to statistically significant improvements in FEV1 (10% change) and FVC (11% change) compared to placebo.
- A significant improvement was also observed in the FEV1/FVC ratio (-2% change) in the camel milk group.
- No changes in medication dosage or frequency were noted, and no side effects were reported with camel milk.
Conclusions:
- Camel milk consumption demonstrates significant benefits for respiratory function in children with cystic fibrosis.
- These findings suggest camel milk can improve the general condition of CF patients.
- Further research is recommended to validate these promising results.
Purpose:
Cystic fibrosis (CF) is a prevalent disease in children that affects respiratory function. There is some evidence suggesting the benefit of camel milk on respiratory function. The present study was carried out to evaluate the effect of camel milk on the spirometry parameters of children with CF.
Patients And Method:
A randomized double-blind clinical trial was operated between 2021 and 2022. Sixty CF children aged more than 6 years were included. The intervention consisted of 300 milliliters of camel milk or cow milk (as a placebo) daily for 2 months. The spirometry parameters and medications were assessed before and 2 months after intervention.
Results:
Sixty patients completed the trial. Patients were similar in baseline characteristics (p > 0.05). Two months after intervention the percentage change in the forced expiratory volume (FEV1) was 10 (2, 31) and -1 (-12, 1) in the intervention and control respectively (p-value < 0.0001). The percentage change in the forced vital capacity (FVC) was 11 (2, 39) and -3 (-17, 1) in the intervention and control respectively (p-value < 0.0001). The percentage change in the FEV1/FVC was -2 (-8, 00) and 0 (-0.5, 5) in the intervention and control respectively (p value = 0.002). The dose and frequency of medication remained unchanged 2 months after the intervention. No camel milk-related side effect was seen.
Conclusion:
Our findings strongly support the benefits of camel milk on respiratory function and the improvement of general conditions in CF patients. More studies are needed to confirm the present evidence.
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