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Successful Salvage of Ventriculoperitoneal Shunt Using Rifampicin in Staphylococcus epidermidis Infection

Yotam D Eshel1, Emily H Kestenbaum2, Keren B Rochwerger2

  • 1Department of Pediatrics Hematology and Oncology, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.

The Israel Medical Association Journal : IMAJ
|October 28, 2025
PubMed
Abstract

No abstract available in PubMed .

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Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

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