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CO2-Lasertonsillotomy Under Local Anesthesia in Adults
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Postoperative sore throat: a systematic review.

Zachary J Moulder1,2, Jason Mann1,2,3, Paul Bramley1,3

  • 1Department of Academic Anaesthesia, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

Anaesthesia
|October 28, 2025
PubMed
Summary
This summary is machine-generated.

Postoperative sore throat affects many patients, but evidence for prevention is limited. Maintaining specific cuff pressures and using certain medications can help reduce its incidence.

Keywords:
anaesthesia, adverse effectsanaesthesia, generalpostoperative sore throatsupraglottic airway devicetracheal intubation

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Area of Science:

  • Anesthesiology
  • Patient Safety
  • Postoperative Care

Background:

  • Postoperative sore throat (POST) is a frequent complication, with an incidence up to 62%.
  • It is a significant cause of patient discomfort and impacts recovery.
  • Current preventative strategies lack robust evidence-based recommendations.

Purpose of the Study:

  • To systematically review interventions aimed at preventing postoperative sore throat.
  • To synthesize evidence on the effectiveness of various preventative measures.
  • To identify areas where further high-quality research is needed.

Main Methods:

  • Systematic review of studies on POST prevention.
  • Two independent reviewers assessed study eligibility and risk of bias.
  • Narrative synthesis due to heterogeneity in study populations, interventions, and outcomes.

Main Results:

  • 162 studies (21,199 patients) were included.
  • Pooled POST incidence at 24 hours was 16.4% for tracheal intubation and 9.9% for supraglottic airway devices.
  • Effective interventions included cuff pressure management (≤60 cmH2O for SGA, ≤30 cmH2O for TT) and specific medications (ketamine, steroids, NSAIDs) for tracheal tubes.

Conclusions:

  • Despite high POST incidence, high-quality trials on prevention are scarce.
  • Effective strategies like cuff pressure control and specific drug use show promise.
  • Future research must address methodological limitations to provide definitive guidance.