Purchases of analgesics before and after spine surgery - register based study of 152,829 Finnish patients with 15-year follow-up
View abstract on PubMed
Summary
This summary is machine-generated.Spine surgery reduced immediate analgesic purchases, but long-term use remained elevated compared to pre-surgery levels. This study analyzed pain medication trends in Finnish patients following spinal procedures.
Area Of Science
- Neurosurgery
- Pain Management
- Health Informatics
Background
- Spine surgery is a common intervention for various spinal conditions.
- Understanding long-term analgesic use post-surgery is crucial for patient outcomes.
- The Finnish PERFECT database offers comprehensive nationwide health data.
Purpose Of The Study
- To evaluate analgesic purchasing patterns before and after spine surgery.
- To compare one-year preoperative and three-year postoperative analgesic use.
- To analyze trends in neuropathic pain medication, NSAIDs, opioids, and acetaminophen.
Main Methods
- Retrospective analysis of 152,829 spine surgery patients from the Finnish PERFECT database.
- Inclusion criteria: degenerative disc disease, disc herniation, spinal stenosis, spondylolysis, or spondylolisthesis.
- Assessment of analgesic purchases (neuropathic pain medication, NSAIDs, opioids, acetaminophen) 15 years pre- and post-surgery.
Main Results
- Overall analgesic purchases decreased compared to the immediate preoperative period.
- Postoperative purchases remained higher than preoperative levels when comparing one year before and three years after surgery.
- Proportions increased for neuropathic pain medication (5-11% to 7-13%) and NSAIDs (4-13% to 5-15%).
- Opioid use increased in DDD, DH, and SS patients (6-12% to 7-14%) but decreased in SPL patients (14% to 12%).
- Acetaminophen use decreased (22-34% to 18-24%).
Conclusions
- Spine surgery leads to a reduction in immediate postoperative analgesic purchases.
- Long-term analgesic use post-spine surgery remains a significant concern.
- Further research is needed to optimize pain management strategies after spinal interventions.
Related Concept Videos
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...

