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Impact of a Nutrition Protocol on Vitamin D Supplementation in a Pediatric Intensive Care Unit: A Retrospective

Maria Pérez Marin1, Vivianne Chanez1, Guillaume Maitre1

  • 1Pediatric Intensive Care Unit, Service of Paediatrics, Women-Mother-Children Department, Lausanne University Hospital, Rue Du Bugnon 21, 1011 Lausanne, Switzerland.

Clinics and Practice
|October 28, 2025
PubMed

Insights

A new nutrition protocol (NP) improved vitamin D supplementation for critically ill children. While more patients received vitamin D, doses for older children and specific formulations presented challenges.

Area of Science:

  • Pediatric Critical Care Medicine
  • Nutritional Support
  • Endocrinology

Background:

  • Vitamin D deficiency (VDD) is common in pediatric intensive care unit (PICU) patients.
  • No universal guidelines exist for vitamin D supplementation in PICU settings.

Purpose of the Study:

  • To evaluate changes in vitamin D supplementation practices.
  • To compare practices before and after implementing a nutrition protocol (NP).

Main Methods:

  • Retrospective analysis of vitamin D administration in children (0-16 years) admitted to a PICU.
  • Data collected included timing, dosage, and adherence to guidelines.
  • Comparison made between the year before and the year after NP introduction.

Main Results:

  • Vitamin D supplementation increased significantly post-NP implementation (95 IU/day more).
  • Higher patient participation (95% vs. 77%) and adherence to NP recommendations for younger children.
  • Supplementation remained below recommended levels for children over one year old.

Conclusions:

  • Implementing a NP substantially improved vitamin D supplementation scope in PICU.
  • Challenges remain in meeting recommended vitamin D requirements due to formulation limitations.
Abstract

Keywords:
nutrition protocolpediatric intensive care unitvitamin D deficiencyvitamin D supplementation

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