Related Experiment Video
Updated: Jan 13, 2026

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
High-Sensitivity Terahertz Biosensor Based on a Multi-Layer Hybrid Structure Consisting of a Defect Mode and Graphene
Hai Hu1, Shiying Mo1, Yangbao Deng1
1All-solid-state Energy Storage Materials and Devices Key Laboratory of Hunan Province, School of Information and Electronic Engineering, Hunan City University, Yiyang 413000, China.
None:
A high-sensitivity terahertz (THz) biosensor is proposed in this paper based on a multi-layer hybrid structure consisting of a defect mode and graphene with a truncation layer. This biosensor is based on symmetrical Bragg reflectors with a defect layer and graphene with a truncation layer, which effectively comprise a multi-layer hybrid resonance excitation structure. The high sensitivity of this biosensor is developed through defect mode resonance, and the resonance reflection peak is made sharper and more sensitive by using graphene with a truncation layer. After testing and analysis, the sensitivity of this biosensor structure is greatly affected by the refractive index and thickness of the sensing medium. By setting parameters appropriately, the composite structure can be used as both a liquid biosensor and a gas biosensor, the maximum sensitivity of which can surpass 2000°/RIU, while an FOM value of 22,500 RIU-1 can be achieved. At the same time, when the refractive index of the liquid sensing medium changes to 0.01 relative to water (the same applies to changes in the gas sensing medium), the sensitivity of this structure still exceeds 600°/RIU, demonstrating that this biosensor has advantages including high sensitivity, a high FOM, wide applicability, and slow sensitivity attenuation. Therefore, the sensing scheme proposed in this paper has potential application prospects in the field of biosensing based on micro/nanostructures due to its simple structure, low requirements for processing conditions, and high sensitivity.
More Related Videos
09:39Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology
Published on: March 31, 2022
09:38Strain Sensing Based on Multiscale Composite Materials Reinforced with Graphene Nanoplatelets
Published on: November 7, 2016