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A scoping review on the neurosequential model.

David Lindenbach1, Panth Desai2, Vanessa Berza3

  • 1Pathways to Prevention: A Centre for Childhood Trauma, Hull Services, Calgary, Alberta, Canada; Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada; Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.

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|October 28, 2025
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Summary

The Neurosequential Model (NM) helps professionals understand how child trauma impacts brain development. This neurodevelopmentally-informed framework supports youth by improving self-regulation and relational engagement, with most studies reporting positive outcomes.

Keywords:
Child traumaComplex traumaDevelopmental traumaNeurosequential modelReal-world evidenceScoping reviewTrauma-informed care

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Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Trauma-Informed Care

Background:

  • Child trauma significantly impacts brain development, leading to adverse health and well-being outcomes.
  • The Neurosequential Model (NM) offers a neurodevelopmentally-informed approach to support children affected by trauma.
  • NM focuses on enhancing self-regulation and relational engagement, guiding assessment, treatment planning, and intervention delivery.

Conclusions:

  • The NM enhances understanding of trauma's effects on brain development and behavior.
  • It aids providers in selecting and implementing interventions tailored to clients' neurodevelopmental needs.
  • The model's primary benefits lie in its ability to inform trauma-informed care strategies.